Medically the review by Alan Carter, Pharm.D. — created by Jill Seladi-Schulman, Ph.D. On December 19, 2018

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Acetaminophen (Tylenol) and ibuprofen (Advil) space both over-the-counter (OTC) drugs that have the right to be provided to relax pain.

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These medications are 2 different varieties of pains relievers. Acetaminophen, sometimes noted as APAP, is its very own type, if ibuprofen is a nonsteroidal anti-inflammatory medicine (NSAID).

Generally, it’s safe to take acetaminophen and ibuprofen together, however you’ll want to salary close fist to just how much you take of each medication.

The an essential to safely acquisition acetaminophen and also ibuprofen is knowing exactly how much you’re taking at a time and also how often.

Acetaminophen dosage

The maximum for sure dosage of acetaminophen for anyone over the age of 12 is 4,000 milligrams (mg) per day. Yet even this amount can harm some people’s livers, therefore aim for no much more than 3,000 mg per day.

For youngsters under the period of 12, it’s finest to inspect with their medical care provider to determine the safest dose for their body weight.

Keep in psychic that numerous OTC drugs contain paracetamol in a selection of doses, generally 325 mg, 500 mg, or 650 mg.

Some instances of brand-name OTC medicines that may contain acetaminophen include:


Remember: as soon as looking at labels, girlfriend might additionally see acetaminophen detailed as APAP.

Ibuprofen dosage

Avoid taking much more that 1,200 mg of ibuprofen in a solitary day. OTC ibuprofen is often uncovered in 200 mg pills. This translates to six pills a day. Still, friend should constantly verify how much is in every pill.

Again, because that children, it’s finest to asking their medical care provider around the safest sheep for your weight.

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If you have actually prescription-strength ibuprofen, speak to her prescriber prior to mixing the with any kind of other medications, consisting of acetaminophen.


The recommended limits for adults and children end 12 are:

3,000 mg per day that acetaminophen1,200 mg every day that ibuprofen

For kids under the period of 12, call their healthcare provider or describe the product label for dosage guidelines.

You can take ibuprofen and acetaminophen in ~ the same time. Just make sure to no take much more than the encourage dose.

Some world experience part stomach or abdominal pain as soon as taking the two drugs together. In this case, it’s far better to alternating when you take it each medication.

For example, you could take ibuprofen first, complied with by acetaminophen four hours later, and also then repeat this process as needed.

You could additionally alternate days. For example, if you take it ibuprofen ~ above Monday, take acetaminophen on Tuesday and so on.